Laurent VALLAT

Mayeur, S., Molitor, A., Miguet, L., Rigolot, L., Naegely, L., Stemmelen, T., Meyer, S., Toussaint, E., Vallat, L., Eischen, A., Chenard, M.-P., Tavian, M., Bahram, S., Carapito, R., & Nicolae, A. (2023). Multiomics of three hematological malignancies in a patient reveal their origin from clonal hematopoietic stem cells. Blood Cancer Journal, 13(1), 118. https://doi.org/10.1038/s41408-023-00892-w

Galland, A., Gourain, V., Habbas, K., Güler, Y., Martin, E., Ebel, C., Tavian, M., Vallat, L., Chenard, M.-P., Mauvieux, L., Freund, J.-N., Duluc, I., & Domon-Dell, C. (2021). CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition. Molecular Oncology. https://doi.org/10.1002/1878-0261.12982

Schleiss, C., Carapito, R., Fornecker, L.-M., Muller, L., Paul, N., Tahar, O., Pichot, A., Tavian, M., Nicolae, A., Miguet, L., Mauvieux, L., Herbrecht, R., Cianferani, S., Freund, J.-N., Carapito, C., Maumy-Bertrand, M., Bahram, S., Bertrand, F., & Vallat, L. (2021). Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia. Leukemia, 35(5), 1463–1474. https://doi.org/10.1038/s41375-021-01221-5

El Omar, R., Julien, E., Biasch, K., Guffroy, B., Lioure, B., Vallat, L., Gross, I., Domon-Dell, C., Lanza, F., Gachet, C., Negroni, M., Freund, J.-N., & Tavian, M. (2021). CDX2 regulates ACE expression in blood development and leukemia cells. Blood Advances, 5(7), 2012–2016. https://doi.org/10.1182/bloodadvances.2020003563

Bertrand, F., Aouadi, I., Jung, N., Carapito, R., Vallat, L., Bahram, S., & Maumy-Bertrand, M. (2020, October 5). SelectBoost: a general algorithm to enhance the performance of variable selection methods. Bioinformatics (Oxford, England). https://doi.org/10.1093/bioinformatics/btaa855

Fornecker, L.-M., Muller, L., Bertrand, F., Paul, N., Pichot, A., Herbrecht, R., Chenard, M.-P., Mauvieux, L., Vallat, L., Bahram, S., Cianférani, S., Carapito, R., & Carapito, C. (2019). Multi-omics dataset to decipher the complexity of drug resistance in diffuse large B-cell lymphoma. Scientific Reports, 9(1), 895. https://doi.org/10.1038/s41598-018-37273-4

Schleiss, C., Ilias, W., Tahar, O., Güler, Y., Miguet, L., Mayeur-Rousse, C., Mauvieux, L., Fornecker, L.-M., Toussaint, E., Herbrecht, R., Bertrand, F., Maumy-Bertrand, M., Martin, T., Fournel, S., Georgel, P., Bahram, S., & Vallat, L. (2019). BCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo. Scientific Reports, 9(1), 701. https://doi.org/10.1038/s41598-018-36853-8

Alsaleh, G., Nehmar, R., Blüml, S., Schleiss, C., Ostermann, E., Dillenseger, J.-P., Sayeh, A., Choquet, P., Dembele, D., Francois, A., Salmon, J.-H., Paul, N., Schabbauer, G., Bierry, G., Meyer, A., Gottenberg, J.-E., Haas, G., Pfeffer, S., Vallat, L., … Georgel, P. (2016). Reduced DICER1 Expression Bestows Rheumatoid Arthritis Synoviocytes Proinflammatory Properties and Resistance to Apoptotic Stimuli. Arthritis & Rheumatology (Hoboken, N.J.), 68(8), 1839–1848. https://doi.org/10.1002/art.39641

Reix, N., Agin, A., Bahram, S., Dali-Youcef, N., Grucker, D., Jaulhac, B., Lepiller, Q., Lessinger, J.-M., Mauvieux, L., Monier, L., Schramm, F., Stoll-Keller, F., Vallat, L., Ludes, B., Candolfi, E., & Filisetti, D. (2015). [Clinical laboratory medicine: continuous amelioration with a book of objectives and satisfaction survey]. Annales De Biologie Clinique, 73(3), 359–368. https://doi.org/10.1684/abc.2015.1045

Le Loarer, F., Barete, S., Vallat, L., Carre, D., El Amarti, R., Torres-Cabala, C., Cacoub, P., Sene, D., Courville, P., & Bravard, P. (2014). Primary cutaneous CD8+ T-cell lymphoma masquerading as acral vascular syndrome. Acta Dermato-Venereologica, 94(3), 317–319. https://doi.org/10.2340/00015555-1670

Jung, N., Bertrand, F., Bahram, S., Vallat, L., & Maumy-Bertrand, M. (2014). Cascade: a R package to study, predict and simulate the diffusion of a signal through a temporal gene network. Bioinformatics (Oxford, England), 30(4), 571–573. https://doi.org/10.1093/bioinformatics/btt705

Vallat, L., Kemper, C. A., Jung, N., Maumy-Bertrand, M., Bertrand, F., Meyer, N., Pocheville, A., Fisher, J. W., Gribben, J. G., & Bahram, S. (2013). Reverse-engineering the genetic circuitry of a cancer cell with predicted intervention in chronic lymphocytic leukemia. Proceedings of the National Academy of Sciences of the United States of America, 110(2), 459–464. https://doi.org/10.1073/pnas.1211130110

Perrot, A., Pionneau, C., Azar, N., Baillou, C., Lemoine, F. M., Leblond, V., Merle-Béral, H., Béné, M.-C., Herbrecht, R., Bahram, S., & Vallat, L. (2012). Waldenström’s macroglobulinemia harbors a unique proteome where Ku70 is severely underexpressed as compared with other B-lymphoproliferative disorders. Blood Cancer Journal, 2, e88. https://doi.org/10.1038/bcj.2012.35

Perrot, A., Pionneau, C., Nadaud, S., Davi, F., Leblond, V., Jacob, F., Merle-Béral, H., Herbrecht, R., Béné, M.-C., Gribben, J. G., Bahram, S., & Vallat, L. (2011). A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia. Blood, 118(4), e1-15. https://doi.org/10.1182/blood-2011-02-335125

Grassin-Delyle, S., Buenestado, A., Vallat, L., Naline, E., Marx, S., Decocq, J., Debré, P., Bernard, O. A., Advenier, C., Devillier, P., & Merle-Béral, H. (2011). Expression and proliferative effect of hemokinin-1 in human B-cells. Peptides, 32(5), 1027–1034. https://doi.org/10.1016/j.peptides.2011.02.012

Marteau, J.-B., Rigaud, O., Brugat, T., Gault, N., Vallat, L., Kruhoffer, M., Orntoft, T. F., Nguyen-Khac, F., Chevillard, S., Merle-Beral, H., & Delic, J. (2010). Concomitant heterochromatinisation and down-regulation of gene expression unveils epigenetic silencing of RELB in an aggressive subset of chronic lymphocytic leukemia in males. BMC Medical Genomics, 3, 53. https://doi.org/10.1186/1755-8794-3-53

Buchner, M., Fuchs, S., Prinz, G., Pfeifer, D., Bartholomé, K., Burger, M., Chevalier, N., Vallat, L., Timmer, J., Gribben, J. G., Jumaa, H., Veelken, H., Dierks, C., & Zirlik, K. (2009). Spleen tyrosine kinase is overexpressed and represents a potential therapeutic target in chronic lymphocytic leukemia. Cancer Research, 69(13), 5424–5432. https://doi.org/10.1158/0008-5472.CAN-08-4252

Praz, F., Le Page, F., Vallat, L., Davi, F., Nguyen-Khac, F., Maloum, K., Delic, J., & Merle-Béral, H. (2008). Absence of microsatellite instability in human chronic lymphocytic leukaemia B cells. Leukemia, 22(1), 186–189. https://doi.org/10.1038/sj.leu.2404889

Vallat, L. D., Park, Y., Li, C., & Gribben, J. G. (2007). Temporal genetic program following B-cell receptor cross-linking: altered balance between proliferation and death in healthy and malignant B cells. Blood, 109(9), 3989–3997. https://doi.org/10.1182/blood-2006-09-045377

Vasconcelos, Y., De Vos, J., Vallat, L., Rème, T., Lalanne, A. I., Wanherdrick, K., Michel, A., Nguyen-Khac, F., Oppezzo, P., Magnac, C., Maloum, K., Ajchenbaum-Cymbalista, F., Troussard, X., Leporrier, M., Klein, B., Dighiero, G., Davi, F., & French Cooperative Group on CLL. (2005). Gene expression profiling of chronic lymphocytic leukemia can discriminate cases with stable disease and mutated Ig genes from those with progressive disease and unmutated Ig genes. Leukemia, 19(11), 2002–2005. https://doi.org/10.1038/sj.leu.2403865

Rigolet, A., Cacoub, P., Schnuriger, A., Vallat, L., Cahour, A., Ghillani, P., Davi, F., Benhamou, Y., Piette, J.-C., & Thibault, V. (2005). Genetic heterogeneity of the hypervariable region I of Hepatitis C virus and lymphoproliferative disorders. Leukemia, 19(6), 1070–1076. https://doi.org/10.1038/sj.leu.2403731

Vallat, L., Benhamou, Y., Gutierrez, M., Ghillani, P., Hercher, C., Thibault, V., Charlotte, F., Piette, J.-C., Poynard, T., Merle-Béral, H., Davi, F., & Cacoub, P. (2004). Clonal B cell populations in the blood and liver of patients with chronic hepatitis C virus infection. Arthritis and Rheumatism, 50(11), 3668–3678. https://doi.org/10.1002/art.20594

Guipaud, O., Deriano, L., Salin, H., Vallat, L., Sabatier, L., Merle-Béral, H., & Delic, J. (2003). B-cell chronic lymphocytic leukaemia: a polymorphic family unified by genomic features. The Lancet. Oncology, 4(8), 505–514.

Vallat, L., Magdelénat, H., Merle-Béral, H., Masdehors, P., Potocki de Montalk, G., Davi, F., Kruhoffer, M., Sabatier, L., Orntoft, T. F., & Delic, J. (2003). The resistance of B-CLL cells to DNA damage-induced apoptosis defined by DNA microarrays. Blood, 101(11), 4598–4606. https://doi.org/10.1182/blood-2002-06-1743