Macrophage depletion overcomes human hematopoietic cell engraftment failure in zebrafish embryo. El Omar R, Abdellaoui N, Coulibaly S, Fontenille L, Lanza F, Gachet C, Freund JN, Negroni M, Kissa K, Tavian M. Cell Death Dis. 2024, accepted Apr 15. / CD32 captures committed haemogenic endothelial cells during human embryonic development. Scarfò R, Randolph LN, Abou…Continue reading 3 recent papers describe studies performed by the Onco-Hematology group in the frame of the UMR-S1113 – IRFAC of Inserm / University of Strasbourg :

The HCERES evaluation report of UMR-S1113 / IRFAC has been published on August 21, 2023 and is available at: https://www.hceres.fr/fr/rechercher-une-publication/irfac-interface-recherche-fondamentale-et-appliquee-en-cancerologie-0. Despite a positive evaluation of the scientific activity, the research unit’s supervisory bodies, Inserm and University of Strasbourg, have decided to close the laboratory definitively on December 31, 2023, for extra-scientific reasons. Jean-Noël Freund, Director…Continue reading Evaluation report and closure of UMR-S1113 / IRFAC

New publication in Arterioscler Thromb Vasc Biol: 2023 Jun 29. doi: 10.1161/ATVBAHA.122.318115. Online ahead of print. MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice Sanjeev Kiran Gotru, Elmina Mammadova-Bach, Georgios Sogkas, Michael K Schuhmann, Karen Schmitt, Peter Kraft, Sabine Herterich, Medina Mamtimin, Akif Pinarci, Sarah Beck, Simon Stritt,…Continue reading 06/29: New publication in Arterioscler Thromb Vasc Biol

The laboratory organized the 40th meeting of the Club for the Study of Digestive Epithelial Cells (CECED) at the dental faculty. The organization, the scientific program and the gala dinner hosted by the famous Relaxed Tarantulas were greatly appreciated by all the participants. The organizing committee warmly thanks all the students of the laboratory for…Continue reading March 21-22, 2023: CECED in Strasbourg

New publication by Susanna SÄISÄ-BORREILL, PhD student from unit U1113. Cell death & differentiation13 january 2023doi: 10.1038/s41418-022-01109-6PMID: 36639541

3 PhD Student (from left to right: Chloé THIBAUDEAU, Sevda RECBERLIK and Mathieu VOGT) have prepared an Advent calendar for the whole unit to enjoy.With this very original Advent calendar, the season of end-of-year festivities is launched at U1113/IRFAC. Thanks to them for this great initiative!

Dr Lucilla Crudele, MD, PhD student in “Metabolism, Aging and Social Medicine” at the University of Bari, Italy, will give a seminar on November-10th at 2 pm in the Bibliothèque of the U1113. The title of the seminar is: Visceral Adiposity and Cancer: prevention and prediction of Hepatocellular Carcinoma and Gender-Specific Cancer

Team 1 : Team 2 :

On the occasion of the last edition of the Fête de la Science (October 7-9, 2022), our doctoral students (Mahassen El-Khoury, Jana Mourtada, Sevda Recberlik, Céline Sieffert, Chloé Thibaudeau, Ourania Vlami, Mathieu Vogt, Mingyi Wu) designed and animated the workshop “From the Molecule to the Patient: Development of Innovative Therapies to Fight Cancer” at the…Continue reading October 7-9, 2022: “Fête de la Science” in Lingolsheim

Giolito MV, La Rosa T, Farhat D, Bodoirat S, Guardia G, Domon-Dell C, Galante P, Freund JN and Plateroti M (2022) Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRa1, in intestinal lesions. Molecular Oncology, doi: 10.1002/1878-0261.13298. In press. Giolito MV and Plateroti M (2022) Thyroid hormone signaling in the intestinal stem…Continue reading 09/2022: 3 new publications