News publications

Gotru, S. K., Mammadova-Bach, E., Sogkas, G., Schuhmann, M. K., Schmitt, K., Kraft, P., Herterich, S., Mamtimin, M., Pinarci, A., Beck, S., Stritt, S., Chao, H., Ren, P., Freund, J.-N., Klemann, C., Ringshausen, F. C., Heemskerk, J. W. M., Dietrich, A., Nieswandt, B., … Braun, A. (2023). MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice. Arteriosclerosis, Thrombosis, and Vascular Biology.
Säisä-Borreill, S., Davidson, G., Kleiber, T., Thevenot, A., Martin, E., Mondot, S., Blottière, H., Helleux, A., Mengus, G., Plateroti, M., Duluc, I., Davidson, I., & Freund, J.-N. (2023). General transcription factor TAF4 antagonizes epigenetic silencing by Polycomb to maintain intestine stem cell functions. Cell Death and Differentiation.
Venkatasamy, A., Guerin, E., Reichardt, W., Devignot, V., Chenard, M. P., Miguet, L., Romain, B., Jung, A. C., Gross, I., Gaiddon, C., & Mellitzer, G. (2022). Morpho-functional analysis of patient-derived xenografts reveals differential impact of gastric cancer and chemotherapy on the tumor ecosystem, affecting immune check point, metabolism, and sarcopenia. Gastric Cancer.
Collard, M. K., Tourneur-Marsille, J., Uzzan, M., Albuquerque, M., Roy, M., Dumay, A., Freund, J.-N., Hugot, J.-P., Guedj, N., Treton, X., Panis, Y., & Ogier-Denis, E. (2022). The appendix orchestrates T-cell mediated immunosurveillance in colitis-associated cancer. Cellular and Molecular Gastroenterology and Hepatology, S2352-345X(22)00230-2.
Giolito, M. V., & Plateroti, M. (2022). Thyroid hormone signaling in the intestinal stem cells and their niche. Cellular and Molecular Life Sciences: CMLS, 79(9), 476.
Goïta, A. A., & Guenot, D. (2022). Colorectal Cancer: The Contribution of CXCL12 and Its Receptors CXCR4 and CXCR7. Cancers, 14(7), 1810.
Passet, M., Kim, R., Gachet, S., Sigaux, F., Chaumeil, J., Galland, A., Sexton, T., Quentin, S., Hernandez, L., Larcher, L., Bergugnat, H., Ye, T., Karasu, N., Caye-Eude, A., Heizmann, B., Duluc, I., Chevallier, P., Rousselot, P., Huguet, F., … Clappier, E. (2022). Concurrent CDX2 cis-deregulation and UBTF-ATXN7L3 fusion define a novel high-risk subtype of B-cell ALL. Blood, blood.2021014723.
Bersuder, E., Terciolo, C., Lechevrel, M., Martin, E., Quesnelle, C., Freund, J.-N., Reimund, J.-M., & Gross, I. (2022). Mesalazine initiates an anti-oncogenic β-catenin / MUCDHL negative feed-back loop in colon cancer cells by cell-specific mechanisms. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 146, 112543.
Delhorme, J.-B., Bersuder, E., Terciolo, C., Vlami, O., Chenard, M.-P., Martin, E., Rohr, S., Brigand, C., Duluc, I., Freund, J.-N., & Gross, I. (2022). CDX2 controls genes involved in the metabolism of 5-fluorouracil and is associated with reduced efficacy of chemotherapy in colorectal cancer. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 147, 112630.
Badie, A., Gaiddon, C., & Mellitzer, G. (2022). Histone Deacetylase Functions in Gastric Cancer: Therapeutic Target? Cancers, 14(21), 5472.
De Azevedo, J., Mourtada, J., Bour, C., Devignot, V., Schultz, P., Borel, C., Pencreach, E., Mellitzer, G., Gaiddon, C., & Jung, A. C. (2022). The EXTREME Regimen Associating Cetuximab and Cisplatin Favors Head and Neck Cancer Cell Death and Immunogenicity with the Induction of an Anti-Cancer Immune Response. Cells, 11(18), 2866.
Sirakov, M., & Plateroti, M. (2022). Thyroid Hormone Signaling and Function: News from Classical and Emerging Models. Cells, 11(3), 453.
Priya, S., Kaur, E., Kulshrestha, S., Pandit, A., Gross, I., Kumar, N., Agarwal, H., Khan, A., Shyam, R., Bhagat, P., Prabhu, J. S., Nagarajan, P., Deo, S. V. S., Bajaj, A., Freund, J.-N., Mukhopadhyay, A., & Sengupta, S. (2021). CDX2 inducible microRNAs sustain colon cancer by targeting multiple DNA damage response pathway factors. Journal of Cell Science, 134(15), jcs258601.
Frau, C., Jamard, C., Delpouve, G., Guardia, G. D. A., Machon, C., Pilati, C., Nevé, C. L., Laurent-Puig, P., Guitton, J., Galante, P. A. F., Penalva, L. O., Freund, J.-N., de la Fouchardiere, C., & Plateroti, M. (2021). Deciphering the Role of Intestinal Crypt Cell Populations in Resistance to Chemotherapy. Cancer Research, 81(10), 2730–2744.
Galland, A., Gourain, V., Habbas, K., Güler, Y., Martin, E., Ebel, C., Tavian, M., Vallat, L., Chenard, M.-P., Mauvieux, L., Freund, J.-N., Duluc, I., & Domon-Dell, C. (2021). CDX2 expression in the hematopoietic lineage promotes leukemogenesis via TGFβ inhibition. Molecular Oncology.
Schleiss, C., Carapito, R., Fornecker, L.-M., Muller, L., Paul, N., Tahar, O., Pichot, A., Tavian, M., Nicolae, A., Miguet, L., Mauvieux, L., Herbrecht, R., Cianferani, S., Freund, J.-N., Carapito, C., Maumy-Bertrand, M., Bahram, S., Bertrand, F., & Vallat, L. (2021). Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia. Leukemia, 35(5), 1463–1474.
Julien, E., Biasch, K., El Omar, R., Freund, J.-N., Gachet, C., Lanza, F., & Tavian, M. (2021). Renin-angiotensin system is involved in embryonic emergence of hematopoietic stem/progenitor cells. Stem Cells (Dayton, Ohio), 39(5), 636–649.
Godart, M., Frau, C., Farhat, D., Giolito, M. V., Jamard, C., Le Nevé, C., Freund, J.-N., Penalva, L. O., Sirakov, M., & Plateroti, M. (2021). Murine intestinal stem cells are highly sensitive to modulation of the T3/TRα1-dependent pathway. Development (Cambridge, England), 148(8), dev194357.
El Omar, R., Julien, E., Biasch, K., Guffroy, B., Lioure, B., Vallat, L., Gross, I., Domon-Dell, C., Lanza, F., Gachet, C., Negroni, M., Freund, J.-N., & Tavian, M. (2021). CDX2 regulates ACE expression in blood development and leukemia cells. Blood Advances, 5(7), 2012–2016.
Giolito, M. V., Claret, L., Frau, C., & Plateroti, M. (2021). A Three-dimensional Model of Spheroids to Study Colon Cancer Stem Cells. JoVE (Journal of Visualized Experiments), 167, e61783.
Baroni, M., Yi, C., Choudhary, S., Lei, X., Kosti, A., Grieshober, D., Velasco, M., Qiao, M., Burns, S. S., Araujo, P. R., DeLambre, T., Son, M. Y., Plateroti, M., Ferreira, M. A. R., Hasty, P., & Penalva, L. O. F. (2021). Musashi1 Contribution to Glioblastoma Development via Regulation of a Network of DNA Replication, Cell Cycle and Division Genes. Cancers, 13(7), 1494.
Sirakov, M., Claret, L., & Plateroti, M. (2021). Thyroid Hormone Nuclear Receptor TRα1 and Canonical WNT Pathway Cross-Regulation in Normal Intestine and Cancer. Frontiers in Endocrinology, 12, 725708.
Gourain, V., Duluc, I., Domon-Dell, C., & Freund, J.-N. (2021). A Core Response to the CDX2 Homeoprotein During Development and in Pathologies. Frontiers in Genetics, 12, 744165.
Boutegrabet, W., Piot, O., Guenot, D., & Gobinet, C. (1753). Unsupervised Feature Selection by a Genetic Algorithm for Mid-Infrared Spectral Data.
Giolito, M. V., La Rosa, T., Farhat, D., Bodoirat, S., Guardia, G. D. A., Domon-Dell, C., Galante, P. A. F., Freund, J.-N., & Plateroti, M. (n.d.). Regulation of the THRA gene, encoding the thyroid hormone nuclear receptor TRα1, in intestinal lesions. Molecular Oncology, n/a(n/a).