Publications Isabelle GROSS before 2013

Hinkel, I., Duluc, I., Martin, E., Guenot, D., Freund, J.-N., & Gross, I. (2012). Cdx2 controls expression of the protocadherin Mucdhl, an inhibitor of growth and β-catenin activity in colon cancer cells. Gastroenterology, 142(4), 875-885.e3. https://doi.org/10.1053/j.gastro.2011.12.037
Renouf, B., Soret, C., Saandi, T., Delalande, F., Martin, E., Vanier, M., … Domon-Dell, C. (2012). Cdx2 homeoprotein inhibits non-homologous end joining in colon cancer but not in leukemia cells. Nucleic Acids Research, 40(8), 3456–3469. https://doi.org/10.1093/nar/gkr1242
Benosman, S., Meng, X., Von Grabowiecki, Y., Palamiuc, L., Hritcu, L., Gross, I., … Gaiddon, C. (2011). Complex regulation of p73 isoforms after alteration of amyloid precursor polypeptide (APP) function and DNA damage in neurons. The Journal of Biological Chemistry, 286(50), 43013–43025. https://doi.org/10.1074/jbc.M111.261271
Martin, E., Vanier, M., Tavian, M., Guerin, E., Domon-Dell, C., Duluc, I., … Freund, J.-N. (2010). CDX2 in congenital gut gastric-type heteroplasia and intestinal-type Meckel diverticula. Pediatrics, 126(3), e723-727. https://doi.org/10.1542/peds.2009-3512
Meng, X., Leyva, M. L., Jenny, M., Gross, I., Benosman, S., Fricker, B., … Gaiddon, C. (2009). A ruthenium-containing organometallic compound reduces tumor growth through induction of the endoplasmic reticulum stress gene CHOP. Cancer Research, 69(13), 5458–5466. https://doi.org/10.1158/0008-5472.CAN-08-4408
Benahmed, F., Gross, I., Gaunt, S. J., Beck, F., Jehan, F., Domon-Dell, C., … Duluc, I. (2008). Multiple regulatory regions control the complex expression pattern of the mouse Cdx2 homeobox gene. Gastroenterology, 135(4), 1238–1247, 1247.e1-3. https://doi.org/10.1053/j.gastro.2008.06.045
Gross, I., Duluc, I., Benameur, T., Calon, A., Martin, E., Brabletz, T., … Freund, J.-N. (2008). The intestine-specific homeobox gene Cdx2 decreases mobility and antagonizes dissemination of colon cancer cells. Oncogene, 27(1), 107–115. https://doi.org/10.1038/sj.onc.1210601
Benosman, S., Gross, I., Clarke, N., Jochemsen, A. G., Okamoto, K., Loeffler, J.-P., & Gaiddon, C. (2007). Multiple neurotoxic stresses converge on MDMX proteolysis to cause neuronal apoptosis. Cell Death and Differentiation, 14(12), 2047–2057. https://doi.org/10.1038/sj.cdd.4402216
Calon, A., Gross, I., Lhermitte, B., Martin, E., Beck, F., Duclos, B., … Freund, J.-N. (2007). Different effects of the Cdx1 and Cdx2 homeobox genes in a murine model of intestinal inflammation. Gut, 56(12), 1688–1695. https://doi.org/10.1136/gut.2007.125542
Gross, I., Armant, O., Benosman, S., de Aguilar, J. L. G., Freund, J.-N., Kedinger, M., … Loeffler, J.-P. (2007). Sprouty2 inhibits BDNF-induced signaling and modulates neuronal differentiation and survival. Cell Death and Differentiation, 14(10), 1802–1812. https://doi.org/10.1038/sj.cdd.4402188
Benahmed, F., Gross, I., Guenot, D., Jehan, F., Martin, E., Domon-Dell, C., … Duluc, I. (2007). The microenvironment controls CDX2 homeobox gene expression in colorectal cancer cells. The American Journal of Pathology, 170(2), 733–744. https://doi.org/10.2353/ajpath.2007.060696
Calon, A., Gross, I., Davidson, I., Kedinger, M., Duluc, I., Domon-Dell, C., & Freund, J.-N. (2007). Functional interaction between the homeoprotein CDX1 and the transcriptional machinery containing the TATA-binding protein. Nucleic Acids Research, 35(1), 175–185. https://doi.org/10.1093/nar/gkl1034
Turck, N., Lefebvre, O., Gross, I., Gendry, P., Kedinger, M., Simon-Assmann, P., & Launay, J.-F. (2006). Effect of laminin-1 on intestinal cell differentiation involves inhibition of nuclear nucleolin. Journal of Cellular Physiology, 206(2), 545–555. https://doi.org/10.1002/jcp.20501
Gross, I., Lhermitte, B., Domon-Dell, C., Duluc, I., Martin, E., Gaiddon, C., … Freund, J.-N. (2005). Phosphorylation of the homeotic tumor suppressor Cdx2 mediates its ubiquitin-dependent proteasome degradation. Oncogene, 24(54), 7955–7963. https://doi.org/10.1038/sj.onc.1208945
Turck, N., Gross, I., Gendry, P., Stutzmann, J., Freund, J.-N., Kedinger, M., … Launay, J.-F. (2005). Laminin isoforms: biological roles and effects on the intracellular distribution of nuclear proteins in intestinal epithelial cells. Experimental Cell Research, 303(2), 494–503. https://doi.org/10.1016/j.yexcr.2004.10.025
Basson, M. A., Akbulut, S., Watson-Johnson, J., Simon, R., Carroll, T. J., Shakya, R., … Licht, J. D. (2005). Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Developmental Cell, 8(2), 229–239. https://doi.org/10.1016/j.devcel.2004.12.004
Mason, J. M., Morrison, D. J., Bassit, B., Dimri, M., Band, H., Licht, J. D., & Gross, I. (2004). Tyrosine phosphorylation of Sprouty proteins regulates their ability to inhibit growth factor signaling: a dual feedback loop. Molecular Biology of the Cell, 15(5), 2176–2188. https://doi.org/10.1091/mbc.e03-07-0503
Gross, I., Morrison, D. J., Hyink, D. P., Georgas, K., English, M. A., Mericskay, M., … Licht, J. D. (2003). The receptor tyrosine kinase regulator Sprouty1 is a target of the tumor suppressor WT1 and important for kidney development. The Journal of Biological Chemistry, 278(42), 41420–41430. https://doi.org/10.1074/jbc.M306425200
Gaiddon, C., Lokshin, M., Gross, I., Levasseur, D., Taya, Y., Loeffler, J.-P., & Prives, C. (2003). Cyclin-dependent kinases phosphorylate p73 at threonine 86 in a cell cycle-dependent manner and negatively regulate p73. The Journal of Biological Chemistry, 278(30), 27421–27431. https://doi.org/10.1074/jbc.M300251200
Gross, I., Bassit, B., Benezra, M., & Licht, J. D. (2001). Mammalian sprouty proteins inhibit cell growth and differentiation by preventing ras activation. The Journal of Biological Chemistry, 276(49), 46460–46468. https://doi.org/10.1074/jbc.M108234200
Hosono, S., Gross, I., English, M. A., Hajra, K. M., Fearon, E. R., & Licht, J. D. (2000). E-cadherin is a WT1 target gene. The Journal of Biological Chemistry, 275(15), 10943–10953.
Gross, I., Georgel, P., Oertel-Buchheit, P., Schnarr, M., & Reichhart, J. M. (1999). Dorsal-B, a splice variant of the Drosophila factor Dorsal, is a novel Rel/NF-kappaB transcriptional activator. Gene, 228(1–2), 233–242.
Gross, I., Georgel, P., Kappler, C., Reichhart, J. M., & Hoffmann, J. A. (1996). Drosophila immunity: a comparative analysis of the Rel proteins dorsal and Dif in the induction of the genes encoding diptericin and cecropin. Nucleic Acids Research, 24(7), 1238–1245.
Georgel, P., Kappler, C., Langley, E., Gross, I., Nicolas, E., Reichhart, J. M., & Hoffmann, J. A. (1995). Drosophila immunity. A sequence homologous to mammalian interferon consensus response element enhances the activity of the diptericin promoter. Nucleic Acids Research, 23(7), 1140–1145.