Raoul HERBRECHT

Schleiss, C., Carapito, R., Fornecker, L.-M., Muller, L., Paul, N., Tahar, O., Pichot, A., Tavian, M., Nicolae, A., Miguet, L., Mauvieux, L., Herbrecht, R., Cianferani, S., Freund, J.-N., Carapito, C., Maumy-Bertrand, M., Bahram, S., Bertrand, F., & Vallat, L. (2021). Temporal multiomic modeling reveals a B-cell receptor proliferative program in chronic lymphocytic leukemia. Leukemia, 35(5), 1463–1474. https://doi.org/10.1038/s41375-021-01221-5

Baldacini, M., Pop, R., Sattler, L., Mauvieux, L., Bilger, K., Gantzer, J., Schneider, F., Beaujeux, R., Simand, C., & Herbrecht, R. (2020). Concomitant hemorrhagic syndrome and recurrent extensive arterial thrombosis in a patient with COVID-19 and acute promyelocytic leukemia. British Journal of Haematology. https://doi.org/10.1111/bjh.16768

Andrès, E., Lorenzo Villalba, N., Mourot-Cottet, R., Maloisel, F., Tebacher, M., Gottenberg, J.-E., Goichot, B., Herbrecht, R., & Zulfiqar, A.-A. (2020). Severe Neutropenia and Agranulocytosis Related to Antithyroid Drugs: A Study of 30 Cases Managed in A Single Reference Center. Medicines (Basel, Switzerland), 7(3). https://doi.org/10.3390/medicines7030015

Herbrecht, R., Guffroy, B., Danion, F., Venkatasamy, A., Simand, C., & Ledoux, M.-P. (2020). Validation by real-life data of the new radiological criteria of the revised and updated consensus definition for invasive fungal diseases. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. https://doi.org/10.1093/cid/ciaa205

Jenks, J. D., Seidel, D., Cornely, O. A., Chen, S., van Hal, S., Kauffman, C., Miceli, M. H., Heinemann, M., Christner, M., Jover Sáenz, A., Burchardt, A., Kemmerling, B., Herbrecht, R., Steinmann, J., Shoham, S., Gräber, S., Pagano, L., Deeren, D., Slavin, M. A., & Hoenigl, M. (2020). Clinical Characteristics and Outcomes of invasive Lomentospora prolificans Infections: Analysis of Patients in the FungiScope® Registry. Mycoses. https://doi.org/10.1111/myc.13067

Lanternier, F., Seidel, D., Pagano, L., Styczynski, J., Mikulska, M., Pulcini, C., Maertens, J., Munoz, P., Garcia, C., Rijnders, B., Arendrup, M. C., Sabino, R., Verissimo, C., Gaustad, P., Klimko, N., Arikan-Akdagli, S., Arsic, V., Barac, A., Skiada, A., … Lortholary, O. (2020). Invasive Pulmonary Aspergillosis treatment duration in haematology patients in Europe: an EFISG, IDWP-EBMT, EORTC-IDG, SEIFEM survey. Mycoses. https://doi.org/10.1111/myc.13056

Ledoux, M.-P., Guffroy, B., Nivoix, Y., Simand, C., & Herbrecht, R. (2020). Invasive Pulmonary Aspergillosis. Seminars in Respiratory and Critical Care Medicine, 41(1), 80–98. https://doi.org/10.1055/s-0039-3401990

Nivoix, Y., Ledoux, M.-P., & Herbrecht, R. (2020). Antifungal Therapy: New and Evolving Therapies. Seminars in Respiratory and Critical Care Medicine, 41(1), 158–174. https://doi.org/10.1055/s-0039-3400291

Jenks, J. D., Seidel, D., Cornely, O. A., Chen, S., van Hal, S., Kauffman, C., Miceli, M. H., Heinemann, M., Christner, M., Sáenz, A. J., Burchardt, A., Kemmerling, B., Herbrecht, R., Steinmann, J., Shoham, S., Gräber, S., Pagano, L., Deeren, D., Aslam, S., … Hoenigl, M. (2020). Voriconazole plus terbinafine combination antifungal therapy for invasive Lomentospora prolificans infections: analysis of 41 patients from the FungiScope® registry 2008-2019. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. https://doi.org/10.1016/j.cmi.2020.01.012

Seidel, D., Hassler, A., Salmanton-García, J., Koehler, P., Mellinghoff, S. C., Carlesse, F., Cheng, M. P., Falces-Romero, I., Herbrecht, R., Jover Sáenz, A., Klimko, N., Mareș, M., Lass-Floerl, C., Soler-Palacín, P., Wisplinghoff, H., Cornely, O. A., Pana, Z., & Lehrnbecher, T. (2019). Invasive Scedosporium spp. and Lomentospora prolificans Infections in Pediatric Patients: Analysis of 55 Cases from FungiScope® and the Literature. International Journal of Infectious Diseases: IJID: Official Publication of the International Society for Infectious Diseases. https://doi.org/10.1016/j.ijid.2019.12.017

Stemler, J., Salmanton-García, J., Seidel, D., Alexander, B., Bertz, H., Hoenigl, M., Herbrecht, R., Meintker, L., Meißner, A., Mellinghoff, S. C., Sal, E., Zarrouk, M., Koehler, P., & Cornely, O. A. (2019). Risk factors and mortality in invasive Rasamsonia spp. infection: Analysis of cases in the FungiScope® registry and from the literature. Mycoses. https://doi.org/10.1111/myc.13039

Garraud, O., Malot, S., Herbrecht, R., Ojeda-Uribe, M., Lin, J.-S., Veyradier, A., Payrat, J.-M., Liu, K., Corash, L., & Coppo, P. (2019). Amotosalen-inactivated fresh frozen plasma is comparable to solvent-detergent inactivated plasma to treat thrombotic thrombocytopenic purpura. Transfusion and Apheresis Science: Official Journal of the World Apheresis Association: Official Journal of the European Society for Haemapheresis, 102665. https://doi.org/10.1016/j.transci.2019.10.007

Salmanton-García, J., Seidel, D., Koehler, P., Mellinghoff, S. C., Herbrecht, R., Klimko, N., Ráčil, Z., Falces-Romero, I., Ingram, P., Benítez-Peñuela, M.-Á., Rodríguez, J. Y., Desoubeaux, G., Barać, A., García-Vidal, C., Hoenigl, M., Mehta, S. R., Cheng, M. P., Klyasova, G., Heinz, W. J., … FungiScope® ECMM/ISHAM Working Group. (2019). Matched-paired analysis of patients treated for invasive mucormycosis: standard treatment versus posaconazole new formulations (MoveOn). The Journal of Antimicrobial Chemotherapy, 74(11), 3315–3327. https://doi.org/10.1093/jac/dkz344

Pang, L., Zhao, X., Dickens, B. L., Lim, J. T., Cook, A. R., Netea, M. G., Donnelly, J. P., Herbrecht, R., Johnson, E. M., Maertens, J. A., Kullberg, B. J., Troke, P. F., Marr, K. A., & Chai, L. Y. A. (2019). Using routine blood parameters to anticipate clinical outcomes in invasive aspergillosis. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. https://doi.org/10.1016/j.cmi.2019.10.019

Schwartz, S., Cornely, O. A., Hamed, K., Marty, F. M., Maertens, J., Rahav, G., Herbrecht, R., & Heinz, W. J. (2019). Isavuconazole for the treatment of patients with invasive fungal diseases involving the central nervous system. Medical Mycology. https://doi.org/10.1093/mmy/myz103

Dubert, M., Le Toriellec, E., Croisille, L., Thomas, L., Ducreux, M., Froissart, A., Herbrecht, R., Lebrun-Vignes, B., Marolleau, J.-P., Méric, J.-B., Mahevas, M., Michel, M., & Bierling, P. (2019). Methylprednisolone-induced immune thrombocytopenia. American Journal of Hematology. https://doi.org/10.1002/ajh.25645

Morel, G., Deau, M.-C., Simand, C., Caye-Eude, A., Arfeuille, C., Ittel, A., Miguet, L., Mauvieux, L., Herbrecht, R., Paillard, C., Strullu, M., Cavé, H., Chan, S., Kastner, P., & Heizmann, B. (2019). Large deletions of the 5’ region of IKZF1 lead to haploinsufficiency in B-cell precursor acute lymphoblastic leukaemia. British Journal of Haematology, 186(5), e155–e159. https://doi.org/10.1111/bjh.15994

El Cheikh, J., Ceballos, P., Dalle, J.-H., Ducastelle-Leprêtre, S., Dulon, E., & Herbrecht, R. (2019). Micafungin prophylaxis in routine medical practice in adult and pediatric patients with hematological malignancy: a prospective, observational study in France. Diagnostic Microbiology and Infectious Disease, 94(3), 268–273. https://doi.org/10.1016/j.diagmicrobio.2019.01.011

Kullberg, B. J., Viscoli, C., Pappas, P. G., Vazquez, J., Ostrosky-Zeichner, L., Rotstein, C., Sobel, J. D., Herbrecht, R., Rahav, G., Jaruratanasirikul, S., Chetchotisakd, P., Van Wijngaerden, E., De Waele, J., Lademacher, C., Engelhardt, M., Kovanda, L., Croos-Dabrera, R., Fredericks, C., & Thompson, G. R. (2019). Isavuconazole Versus Caspofungin in the Treatment of Candidemia and Other Invasive Candida Infections: The ACTIVE Trial. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 68(12), 1981–1989. https://doi.org/10.1093/cid/ciy827

Cornu, M., Sendid, B., Mery, A., François, N., Malgorzata, M., Letscher-Bru, V., De Carolis, E., Damonti, L., Titecat, M., Bochud, P.-Y., Alanio, A., Sanguinetti, M., Viscoli, C., Herbrecht, R., Guerardel, Y., & Poulain, D. (2019). Evaluation of Mass Spectrometry-Based Detection of Panfungal Serum Disaccharide for Diagnosis of Invasive Fungal Infections: Results from a Collaborative Study Involving Six European Clinical Centers. Journal of Clinical Microbiology, 57(5), e01867-18. https://doi.org/10.1128/JCM.01867-18

Fornecker, L.-M., Muller, L., Bertrand, F., Paul, N., Pichot, A., Herbrecht, R., Chenard, M.-P., Mauvieux, L., Vallat, L., Bahram, S., Cianférani, S., Carapito, R., & Carapito, C. (2019). Multi-omics dataset to decipher the complexity of drug resistance in diffuse large B-cell lymphoma. Scientific Reports, 9(1), 895. https://doi.org/10.1038/s41598-018-37273-4

Schleiss, C., Ilias, W., Tahar, O., Güler, Y., Miguet, L., Mayeur-Rousse, C., Mauvieux, L., Fornecker, L.-M., Toussaint, E., Herbrecht, R., Bertrand, F., Maumy-Bertrand, M., Martin, T., Fournel, S., Georgel, P., Bahram, S., & Vallat, L. (2019). BCR-associated factors driving chronic lymphocytic leukemia cells proliferation ex vivo. Scientific Reports, 9(1), 701. https://doi.org/10.1038/s41598-018-36853-8

Lescuyer, S., Ledoux, M.-P., Gravier, S., Natarajan-Amé, S., Duval, C., Maloisel, F., Mauvieux, L., Toussaint, E., Fornecker, L.-M., & Herbrecht, R. (2019). Tuberculosis and atypical mycobacterial infections in ruxolitinib-treated patients with primary or secondary myelofibrosis or polycythemia vera. International Journal of Infectious Diseases: IJID: Official Publication of the International Society for Infectious Diseases, 80, 134–136. https://doi.org/10.1016/j.ijid.2019.01.002

Seidel, D., Meißner, A., Lackner, M., Piepenbrock, E., Salmanton-García, J., Stecher, M., Mellinghoff, S., Hamprecht, A., Durán Graeff, L., Köhler, P., Cheng, M. P., Denis, J., Chedotal, I., Chander, J., Pakstis, D. L., Los-Arcos, I., Slavin, M., Montagna, M. T., Caggiano, G., … Vermeulen, E. (2019). Prognostic factors in 264 adults with invasive Scedosporium spp. and Lomentospora prolificans infection reported in the literature and FungiScope®. Critical Reviews in Microbiology, 1–21. https://doi.org/10.1080/1040841X.2018.1514366

Herbrecht, R., Kuessner, D., Pooley, N., Posthumus, J., & Escrig, C. (2018). Systematic review and network meta-analysis of clinical outcomes associated with isavuconazole versus relevant comparators for patients with invasive aspergillosis. Current Medical Research and Opinion, 34(12), 2187–2195. https://doi.org/10.1080/03007995.2018.1502659

Maertens, J., Selleslag, D., Heinz, W. J., Saulay, M., Rahav, G., Giladi, M., Aoun, M., Kovanda, L., Kaufhold, A., Engelhardt, M., Cornely, O. A., Herbrecht, R., & Ullmann, A. J. (2018). Treatment outcomes in patients with proven/probable vs possible invasive mould disease in a phase III trial comparing isavuconazole vs voriconazole. Mycoses, 61(11), 868–876. https://doi.org/10.1111/myc.12831

Shi, Q., Schmitz, N., Ou, F.-S., Dixon, J. G., Cunningham, D., Pfreundschuh, M., Seymour, J. F., Jaeger, U., Habermann, T. M., Haioun, C., Tilly, H., Ghesquieres, H., Merli, F., Ziepert, M., Herbrecht, R., Flament, J., Fu, T., Coiffier, B., & Flowers, C. R. (2018). Progression-Free Survival as a Surrogate End Point for Overall Survival in First-Line Diffuse Large B-Cell Lymphoma: An Individual Patient-Level Analysis of Multiple Randomized Trials (SEAL). Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology, 36(25), 2593–2602. https://doi.org/10.1200/JCO.2018.77.9124

Gangneux, J.-P., El Cheikh, J., Herbrecht, R., Yakoub-Agha, I., Quiniou, J.-B., Caillot, D., & Michallet, M. (2018). Systemic Antifungal Prophylaxis in Patients Hospitalized in Hematology Units in France: The AFHEM Cross-Sectional Observational Study. Infectious Diseases and Therapy, 7(3), 309–325. https://doi.org/10.1007/s40121-018-0203-4

Maurer, M. J., Habermann, T. M., Shi, Q., Schmitz, N., Cunningham, D., Pfreundschuh, M., Seymour, J. F., Jaeger, U., Haioun, C., Tilly, H., Ghesquieres, H., Merli, F., Ziepert, M., Herbrecht, R., Flament, J., Fu, T., Flowers, C. R., & Coiffier, B. (2018). Progression-free survival at 24 months (PFS24) and subsequent outcome for patients with diffuse large B-cell lymphoma (DLBCL) enrolled on randomized clinical trials. Annals of Oncology: Official Journal of the European Society for Medical Oncology, 29(8), 1822–1827. https://doi.org/10.1093/annonc/mdy203

Herbrecht, R., Ojeda-Uribe, M., Kientz, D., Fohrer, C., Bohbot, A., Hinschberger, O., Liu, K.-L., Remy, E., Ernst, C., Lin, J.-S., Corash, L., & Cazenave, J. P. (2018). Characterization of efficacy and safety of pathogen inactivated and quarantine plasma in routine use for treatment of acquired immune thrombotic thrombocytopenic purpura. Vox Sanguinis, 15(5), 459–467. https://doi.org/10.1111/vox.12663

Ullmann, A. J., Aguado, J. M., Arikan-Akdagli, S., Denning, D. W., Groll, A. H., Lagrou, K., Lass-Flörl, C., Lewis, R. E., Munoz, P., Verweij, P. E., Warris, A., Ader, F., Akova, M., Arendrup, M. C., Barnes, R. A., Beigelman-Aubry, C., Blot, S., Bouza, E., Brüggemann, R. J. M., … Cornely, O. A. (2018). Diagnosis and management of Aspergillus diseases: executive summary of the 2017 ESCMID-ECMM-ERS guideline. Clinical Microbiology and Infection: The Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 24 Suppl 1, e1–e38. https://doi.org/10.1016/j.cmi.2018.01.002

Denis, J., Forouzanfar, F., Herbrecht, R., Toussaint, E., Kessler, R., Sabou, M., Candolfi, E., & Letsher-Bru, V. (2018). Evaluation of Two Commercial Real-Time PCR Kits for Aspergillus DNA Detection in Bronchoalveolar Lavage Fluid in Patients with Invasive Pulmonary Aspergillosis. The Journal of Molecular Diagnostics: JMD, 20(3), 298–306. https://doi.org/10.1016/j.jmoldx.2017.12.005

Ledoux, M.-P., Denis, J., Nivoix, Y., & Herbrecht, R. (2018). Isavuconazole: A new broad-spectrum azole. Part 2: pharmacokinetics and clinical activity. Journal De Mycologie Medicale, 28(1), 15–22. https://doi.org/10.1016/j.mycmed.2018.02.002

Goh, J. G., Ravikumar, S., Win, M. S., Cao, Q., Tan, A. L., Lim, J. H. J., Leong, W., Herbrecht, R., Troke, P. F., Kullberg, B. J., Netea, M. G., Chng, W. J., Dan, Y. Y., & Chai, L. Y. A. (2018). Neutrophils differentially attenuate immune response to Aspergillus infection through complement receptor 3 and induction of myeloperoxidase. Cellular Microbiology, 20(3), e12798. https://doi.org/10.1111/cmi.12798

Denis, J., Ledoux, M.-P., Nivoix, Y., & Herbrecht, R. (2018). Isavuconazole: A new broad-spectrum azole. Part 1: In vitro activity. Journal De Mycologie Medicale, 28(1), 8–14. https://doi.org/10.1016/j.mycmed.2018.02.005

Alhosin, M., León-González, A. J., Dandache, I., Lelay, A., Rashid, S. K., Kevers, C., Pincemail, J., Fornecker, L.-M., Mauvieux, L., Herbrecht, R., & Schini-Kerth, V. B. (2015). Bilberry extract (Antho 50) selectively induces redox-sensitive caspase 3-related apoptosis in chronic lymphocytic leukemia cells by targeting the Bcl-2/Bad pathway. Scientific Reports, 5, 8996. https://doi.org/10.1038/srep08996

Duval, C., Boucher, S., Moulin, J.-C., Gourieux, B., Mauvieux, L., Leveque, D., & Herbrecht, R. (2014). Fatal stimulation of acute myeloid leukemia blasts by pegfilgrastim. Anticancer Research, 34(11), 6747–6748.

Miguet, L., Lennon, S., Baseggio, L., Traverse-Glehen, A., Berger, F., Perrusson, N., Chenard, M.-P., Galoisy, A.-C., Eischen, A., Mayeur-Rousse, C., Maar, A., Fornecker, L., Herbrecht, R., Felman, P., Van Dorsselaer, A., Carapito, C., Cianférani, S., & Mauvieux, L. (2013). Cell-surface expression of the TLR homolog CD180 in circulating cells from splenic and nodal marginal zone lymphomas. Leukemia, 27(8), 1748–1750. https://doi.org/10.1038/leu.2013.3

Gervais, C., Dano, L., Perrusson, N., Hélias, C., Jeandidier, E., Galoisy, A.-C., Ittel, A., Herbrecht, R., Bilger, K., & Mauvieux, L. (2013). A translocation t(2;8)(q12;p11) fuses FGFR1 to a novel partner gene, RANBP2/NUP358, in a myeloproliferative/myelodysplastic neoplasm. Leukemia, 27(5), 1186–1188. https://doi.org/10.1038/leu.2012.286

Dupuis, A., Gaub, M. P., Legrain, M., Drenou, B., Mauvieux, L., Lutz, P., Herbrecht, R., Chan, S., & Kastner, P. (2013). Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations. Leukemia, 27(2), 503–507. https://doi.org/10.1038/leu.2012.204

Perrot, A., Pionneau, C., Azar, N., Baillou, C., Lemoine, F. M., Leblond, V., Merle-Béral, H., Béné, M.-C., Herbrecht, R., Bahram, S., & Vallat, L. (2012). Waldenström’s macroglobulinemia harbors a unique proteome where Ku70 is severely underexpressed as compared with other B-lymphoproliferative disorders. Blood Cancer Journal, 2, e88. https://doi.org/10.1038/bcj.2012.35

Perrot, A., Pionneau, C., Nadaud, S., Davi, F., Leblond, V., Jacob, F., Merle-Béral, H., Herbrecht, R., Béné, M.-C., Gribben, J. G., Bahram, S., & Vallat, L. (2011). A unique proteomic profile on surface IgM ligation in unmutated chronic lymphocytic leukemia. Blood, 118(4), e1-15. https://doi.org/10.1182/blood-2011-02-335125

Miguet, L., Béchade, G., Fornecker, L., Zink, E., Felden, C., Gervais, C., Herbrecht, R., Van Dorsselaer, A., van Dorsselaer, A., Mauvieux, L., & Sanglier-Cianferani, S. (2009). Proteomic analysis of malignant B-cell derived microparticles reveals CD148 as a potentially useful antigenic biomarker for mantle cell lymphoma diagnosis. Journal of Proteome Research, 8(7), 3346–3354. https://doi.org/10.1021/pr801102c

Struski, S., Gervais, C., Helias, C., Herbrecht, R., Audhuy, B., & Mauvieux, L. (2009). Stimulation of B-cell lymphoproliferations with CpG-oligonucleotide DSP30 plus IL-2 is more effective than with TPA to detect clonal abnormalities. Leukemia, 23(3), 617–619. https://doi.org/10.1038/leu.2008.252

Nivoix, Y., Velten, M., Letscher-Bru, V., Moghaddam, A., Natarajan-Amé, S., Fohrer, C., Lioure, B., Bilger, K., Lutun, P., Marcellin, L., Launoy, A., Freys, G., Bergerat, J.-P., & Herbrecht, R. (2008). Factors associated with overall and attributable mortality in invasive aspergillosis. Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America, 47(9), 1176–1184. https://doi.org/10.1086/592255

Hélias, C., Struski, S., Gervais, C., Leymarie, V., Mauvieux, L., Herbrecht, R., & Lessard, M. (2008). Polycythemia vera transforming to acute myeloid leukemia and complex abnormalities including 9p homogeneously staining region with amplification of MLLT3, JMJD2C, JAK2, and SMARCA2. Cancer Genetics and Cytogenetics, 180(1), 51–55. https://doi.org/10.1016/j.cancergencyto.2007.09.010