Alain JUNG


ORCID – ResearcherID

(+33) 03 88 27 53 67

Liste des publications :

Spaety, M.-E., Gries, A., Badie, A., Venkatasamy, A., Romain, B., Orvain, C., Yanagihara, K., Okamoto, K., Jung, A. C., Mellitzer, G., Pfeffer, S., & Gaiddon, C. (2019). HDAC4 Levels Control Sensibility toward Cisplatin in Gastric Cancer via the p53-p73/BIK Pathway. Cancers, 11(11), 1747.
Coliat, P., Ramolu, L., Jégu, J., Gaiddon, C., Jung, A. C., & Pencreach, E. (2019). Constitutive or Induced HIF-2 Addiction is Involved in Resistance to Anti-EGFR Treatment and Radiation Therapy in HNSCC. Cancers, 11(10).
Job, S., Reyniès, A. de, Heller, B., Weiss, A., Guérin, E., Macabre, C., Ledrappier, S., Bour, C., Wasylyk, C., Etienne-Selloum, N., Brino, L., Gaiddon, C., Wasylyk, B., & Jung, A. C. (2019). Preferential Response of Basal-Like Head and Neck Squamous Cell Carcinoma Cell Lines to EGFR-Targeted Therapy Depending on EREG-Driven Oncogenic Addiction. Cancers, 11(6).
Vidimar, V., Licona, C., Cerón-Camacho, R., Guerin, E., Coliat, P., Venkatasamy, A., Ali, M., Guenot, D., Le Lagadec, R., Jung, A. C., Freund, J.-N., Pfeffer, M., Mellitzer, G., Sava, G., & Gaiddon, C. (2019). A redox ruthenium compound directly targets PHD2 and inhibits the HIF1 pathway to reduce tumor angiogenesis independently of p53. Cancer Letters, 440–441, 145–155.
Borel, C., Regnier-Gavier, O., Carinato, H., Guihard, S., Antoni, D., Demarchi, M., Sirlin, F., Exinger, D., Petit-Jean, E., Thiery, A., Bronner, G., Schultz, P., Flesch, H., Frasie, V., Prébay, D., Petit, T., Jung, A. C., Burgy, M., & Coliat, P. (2018). Interest to consider re-challenging by cetuximab and platinum containing regimen in recurrent Head and Neck Cancer. Oncotarget, 9(101), 37581–37588.
Mirghani, H., Jung, A. C., & Fakhry, C. (2017). Primary, secondary and tertiary prevention of human papillomavirus-driven head and neck cancers. European Journal of Cancer (Oxford, England: 1990), 78, 105–115.
Bonnin, N., Armandy, E., Carras, J., Ferrandon, S., Battiston-Montagne, P., Aubry, M., Guihard, S., Meyronet, D., Foy, J.-P., Saintigny, P., Ledrappier, S., Jung, A. C., Rimokh, R., Rodriguez-Lafrasse, C., & Poncet, D. (2016). MiR-422a promotes loco-regional recurrence by targeting NT5E/CD73 in head and neck squamous cell carcinoma. Oncotarget, 7(28), 44023–44038.
Jung, A. C., Ray, A.-M., Ramolu, L., Macabre, C., Simon, F., Noulet, F., Blandin, A.-F., Renner, G., Lehmann, M., Choulier, L., Kessler, H., Abecassis, J., Dontenwill, M., & Martin, S. (2015). Caveolin-1-negative head and neck squamous cell carcinoma primary tumors display increased epithelial to mesenchymal transition and prometastatic properties. Oncotarget, 6(39), 41884–41901.
Hanns, E., Job, S., Coliat, P., Wasylyk, C., Ramolu, L., Pencreach, E., Suarez-Carmona, M., Herfs, M., Ledrappier, S., Macabre, C., Abecassis, J., Wasylyk, B., & Jung, A. C. (2015). Human Papillomavirus-related tumours of the oropharynx display a lower tumour hypoxia signature. Oral Oncology, 51(9), 848–856.
Chamard-Jovenin, C., Jung, A. C., Chesnel, A., Abecassis, J., Flament, S., Ledrappier, S., Macabre, C., Boukhobza, T., & Dumond, H. (2015). From ERα66 to ERα36: a generic method for validating a prognosis marker of breast tumor progression. BMC Systems Biology, 9, 28.
Robertson, E. D., Wasylyk, C., Ye, T., Jung, A. C., & Wasylyk, B. (2014). The oncogenic MicroRNA Hsa-miR-155-5p targets the transcription factor ELK3 and links it to the hypoxia response. PloS One, 9(11), e113050.
Wasylyk, B., Abecassis, J., & Jung, A. C. (2013). Identification of clinically relevant HPV-related HNSCC: in p16 should we trust? Oral Oncology, 49(10), e33-37.
Ennen, M., Klotz, R., Touche, N., Pinel, S., Barbieux, C., Besancenot, V., Brunner, E., Thiebaut, D., Jung, A. C., Ledrappier, S., Domenjoud, L., Abecassis, J., Plénat, F., Grandemange, S., & Becuwe, P. (2013). DDB2: a novel regulator of NF-κB and breast tumor invasion. Cancer Research, 73(16), 5040–5052.
Jung, A. C., Job, S., Ledrappier, S., Macabre, C., Abecassis, J., de Reyniès, A., & Wasylyk, B. (2013). A poor prognosis subtype of HNSCC is consistently observed across methylome, transcriptome, and miRNome analysis. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research, 19(15), 4174–4184.
Jung, A. C. (2013). Can liberating p53 from E6 free patients from HPV-related head and neck tumors? Cell Cycle (Georgetown, Tex.), 12(6), 868.
Jung, A. C., Guihard, S., Krugell, S., Ledrappier, S., Brochot, A., Dalstein, V., Job, S., de Reynies, A., Noël, G., Wasylyk, B., Clavel, C., & Abecassis, J. (2013). CD8-alpha T-cell infiltration in human papillomavirus-related oropharyngeal carcinoma correlates with improved patient prognosis. International Journal of Cancer, 132(2), E26-36.
Guihard, S., Ramolu, L., Macabre, C., Wasylyk, B., Noël, G., Abecassis, J., & Jung, A. C. (2012). The NEDD8 conjugation pathway regulates p53 transcriptional activity and head and neck cancer cell sensitivity to ionizing radiation. International Journal of Oncology, 41(4), 1531–1540.
Guihard, S., Jung, A. C., & Noël, G. (2012). [High-risk human papilloma virus associated oropharynx squamous cell carcinomas: clinical, biological implications and therapeutical perspectives]. Cancer Radiotherapie: Journal De La Societe Francaise De Radiotherapie Oncologique, 16(1), 34–43.
Chanut-Delalande, H., Jung, A. C., Baer, M. M., Lin, L., Payre, F., & Affolter, M. (2010). The Hrs/Stam complex acts as a positive and negative regulator of RTK signaling during Drosophila development. PloS One, 5(4), e10245.
Jung, A. C., Briolat, J., Millon, R., Reyniès, A. de, Rickman, D., Thomas, E., Abecassis, J., Clavel, C., & Wasylyk, B. (2010). Biological and clinical relevance of transcriptionally active human papillomavirus (HPV) infection in oropharynx squamous cell carcinoma. International Journal of Cancer, 126(8), 1882–1894.
Altmeyer, A., Jung, A. C., Ignat, M., Benzina, S., Denis, J.-M., Gueulette, J., Noël, G., Mutter, D., & Bischoff, P. (2010). Pharmacological enhancement of autophagy induced in a hepatocellular carcinoma cell line by high-LET radiation. Anticancer Research, 30(2), 303–310.
Chanut-Delalande, H., Jung, A. C., Lin, L., Baer, M. M., Bilstein, A., Cabernard, C., Leptin, M., & Affolter, M. (2007). A genetic mosaic analysis with a repressible cell marker screen to identify genes involved in tracheal cell migration during Drosophila air sac morphogenesis. Genetics, 176(4), 2177–2187.
Jung, A. C., Ribeiro, C., Michaut, L., Certa, U., & Affolter, M. (2006). Polychaetoid/ZO-1 is required for cell specification and rearrangement during Drosophila tracheal morphogenesis. Current Biology: CB, 16(12), 1224–1231.
Jung, A. C., Denholm, B., Skaer, H., & Affolter, M. (2005). Renal tubule development in Drosophila: a closer look at the cellular level. Journal of the American Society of Nephrology: JASN, 16(2), 322–328.
Jung, A. C., Criqui, M. C., Rutschmann, S., Hoffmann, J. A., & Ferrandon, D. (2001). Microfluorometer assay to measure the expression of beta-galactosidase and green fluorescent protein reporter genes in single Drosophila flies. BioTechniques, 30(3), 594–598, 600–601.
Rutschmann, S., Jung, A. C., Zhou, R., Silverman, N., Hoffmann, J. A., & Ferrandon, D. (2000). Role of Drosophila IKK gamma in a toll-independent antibacterial immune response. Nature Immunology, 1(4), 342–347.
Rutschmann, S., Jung, A. C., Hetru, C., Reichhart, J. M., Hoffmann, J. A., & Ferrandon, D. (2000). The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila. Immunity, 12(5), 569–580.
Ferrandon, D., Jung, A. C., Criqui, M., Lemaitre, B., Uttenweiler-Joseph, S., Michaut, L., Reichhart, J., & Hoffmann, J. A. (1998). A drosomycin-GFP reporter transgene reveals a local immune response in Drosophila that is not dependent on the Toll pathway. The EMBO Journal, 17(5), 1217–1227.